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This Spicy Southwest Meatloaf is a hit with my family! The Ro-Tel tomatoes and chili sauce give it a nice spice without making it too hot.

Spicy Southwest Meatloaf with green beans and taco tatos on plate.

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Spicy Southwest Meatloaf

Meatloaf seems to be one of those foods that people either love it or they hate it. There really isn’t any middle ground, is there? My family enjoys meatloaf – Dare I say, they actually look forward to it? I probably have 10 or 15 different meatloaves that I have made over the years. While the traditional meatloaf with the ketchup topping is nice and comforting, sometimes it’s nice to shake things up a bit.

We served our Spicy Southwest Meatloaf up with some Taco Tatoes and green beans. Cornbread muffins on the side would be a nice accompaniment! If you’re looking to kick your regular ol’ meatloaf up a notch, definitely give this recipe a try – you’ll be glad you did!

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spicy southwest meatloaf on white plate with green beans and potatoes
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Servings: 10 servings

Spicy Southwest Meatloaf

By Jamie Sherman
This Spicy Southwest Meatloaf is a hit with my family! It’s not too spicy, but the Ro-Tel tomatoes and chili sauce give it a nice spice without making it too hot.
Prep: 20 minutes
Cook: 1 hour
Total: 1 hour 20 minutes

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Ingredients 

  • 2 pounds lean ground beef
  • 3 slices bread, torn into small pieces
  • ½ small onion, finely chopped
  • ½ cup green pepper, finely chopped
  • 1 can Ro-Tel Original Diced Tomatoes & Green Chilies, slightly drained, 10 oz.
  • 2 large eggs, beaten
  • 2 teaspoons chili powder
  • ½ – ¾ cup chili sauce

Instructions 

  • Preheat oven to 400°F.
  • Combine the beef, bread, onions, green pepper, tomatoes, eggs, and chili powder in a medium bowl. Shape the meat mixture into a loaf. Place in an ungreased 8½x4½x2½-inch loaf pan.
  • Bake for 45-55 minutes or until the meat is no longer pink in the middle. Carefully drain.
  • Spoon the chili sauce over the top of the meatloaf and bake for an additional 10 minutes.
  • Allow to stand for 5 minutes before slicing.
  • Serve.

Notes

  • Cornbread muffins on the side would be a nice accompaniment!

Nutrition

Calories: 185kcal, Carbohydrates: 9g, Protein: 22g, Fat: 6g, Saturated Fat: 2g, Polyunsaturated Fat: 1g, Monounsaturated Fat: 2g, Trans Fat: 0.3g, Cholesterol: 93mg, Sodium: 308mg, Potassium: 493mg, Fiber: 1g, Sugar: 4g, Vitamin A: 341IU, Vitamin C: 12mg, Calcium: 43mg, Iron: 3mg

Nutrition information is automatically calculated, so should only be used as an approximation.

Like this? Leave a comment below!

Originally published on June 27, 2013. Updated on April 23, 2021.

Jamie

Jamie Sherman founded Love Bakes Good Cakes in February 2012. She is a self-taught home cook passionate about sharing easy, delicious, and family-friendly recipes. From comforting classics to irresistible desserts, I believe homemade food brings people together. Join me on my journey of creating and sharing meals that bring joy to every table!

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11 Comments

  1. Sheena @ Hot Eats and Cool Reads says:

    This sounds so good, Jamie! Pinning!

  2. Michelle says:

    Meatloaf is something I didn't like as a child, but I sure do now. Love the ro-tel in this! Thank you for coming by this evening and sharing this spicy meatloaf, Jamie.
    Michelle @Ms. enPlace

  3. Susan@Organized31 says:

    i love meatloaf. My family loves spicy. Maybe I can sway them over to liking meatloaf too with your take on it. Thanks for sharing at Inspire Us Thursday.

  4. Claire @ A Little Claireification says:

    YUM!! Always love having you at the party, Jamie!! xoxo

  5. Cindy Eikenberg, Little Miss Celebration says:

    Jamie, this looks so delicious!!! Thank you so much for sharing with us at Best of the Weekend!

  6. Adelina Priddis says:

    Looks awesome. Meatloaf is one reason my husband and I came together. We found out early on that we both love meatloaf. A match made in heaven 🙂
    Thanks for sharing on Foodie Friday!

  7. Eric Pepple says:

    Nothing beats a good meatloaf and this definitely sounds like a winner! Such a great comfort food 🙂

    Happy Blogging!
    Happy Valley Chow

  8. Joy says:

    Oooo, I love the seasonings in this- ro-tel, chili sauce…you just KNOW it's going to be good!

  9. Rhondda Mol says:

    My husband LOVES meatloaf and this looks delicious! So do so many other recipes you have on your blog 🙂 Thank you for sharing at 'The Project Stash' – where I just found you – now I am following along for more good 'eats'!
    Rhondda

  10. Linda @ With A Blast says:

    I think I've made one meatloaf in my life ! Your recipe will have to be tested 😉 The Taco Tatoes looks great too !