Spicy Southwest Meatloaf

This Spicy Southwest Meatloaf is a hit with my family! The Ro-Tel tomatoes and chili sauce give it a nice spice without making it too hot.

Spicy Southwest Meatloaf

Meatloaf seems to be one of those foods that people either love it or they hate it. There really isn’t any middle ground, is there? My family enjoys meatloaf – Dare I say, they actually look forward to it? I probably have 10 or 15 different meatloaves that I have made over the years. While the traditional meatloaf with the ketchup topping is nice and comforting, sometimes it’s nice to shake things up a bit.

We served our Spicy Southwest Meatloaf up with some Taco Tatoes and green beans. Cornbread muffins on the side would be a nice accompaniment! If you’re looking to kick your regular ol’ meatloaf up a notch, definitely give this recipe a try – you’ll be glad you did!

Other recipes you may enjoy

• Italian-Style Meatloaf
• Meatloaf Muffins
• Simple Southwest Chicken & Rice Soup
• Southwest Cheeseburger
• Southwest Potato Soup

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Servings: 10 servings

Spicy Southwest Meatloaf

By Jamie Sherman

This Spicy Southwest Meatloaf is a hit with my family! It’s not too spicy, but the Ro-Tel tomatoes and chili sauce give it a nice spice without making it too hot.

Prep: 20 minutes mins

Cook: 1 hour hr

Total: 1 hour hr 20 minutes mins

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Ingredients 

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• ▢ 2 pounds lean ground beef
• ▢ 3 slices bread, torn into small pieces
• ▢ ½ small onion, finely chopped
• ▢ ½ cup green pepper, finely chopped
• ▢ 1 can Ro-Tel Original Diced Tomatoes & Green Chilies, slightly drained, 10 oz.
• ▢ 2 large eggs, beaten
• ▢ 2 teaspoons chili powder
• ▢ ½ – ¾ cup chili sauce

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Instructions 

• Preheat oven to 400°F.
• Combine the beef, bread, onions, green pepper, tomatoes, eggs, and chili powder in a medium bowl. Shape the meat mixture into a loaf. Place in an ungreased 8½x4½x2½-inch loaf pan.
• Bake for 45-55 minutes or until the meat is no longer pink in the middle. Carefully drain.
• Spoon the chili sauce over the top of the meatloaf and bake for an additional 10 minutes.
• Allow to stand for 5 minutes before slicing.
• Serve.

Notes

• Cornbread muffins on the side would be a nice accompaniment!

Nutrition

Calories: 185kcal, Carbohydrates: 9g, Protein: 22g, Fat: 6g, Saturated Fat: 2g, Polyunsaturated Fat: 1g, Monounsaturated Fat: 2g, Trans Fat: 0.3g, Cholesterol: 93mg, Sodium: 308mg, Potassium: 493mg, Fiber: 1g, Sugar: 4g, Vitamin A: 341IU, Vitamin C: 12mg, Calcium: 43mg, Iron: 3mg

Nutrition information is automatically calculated, so should only be used as an approximation.

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Originally published on June 27, 2013. Updated on April 23, 2021.