In a large bowl, combine the ground venison, brown sugar, ketchup, Worcestershire sauce, garlic powder, onion powder, salt, and pepper until fully combined. Do not overmix.
Divide the meat mixture into 6 even-sized patties. Make a small indention in the center of each patty and place them on a sheet tray until you are ready to grill.
Preheat the grill over medium-high heat. Lightly oil the grates. Place the burgers on the grill without them touching for about 3-5 minutes per side or until they reach your desired doneness. Flip the burgers and continue cooking for another 3-5 minutes or until your desired doneness.
If you are using cheese: A couple of minutes before the burgers are ready, add a slice of cheese on top. Close the grill and let the cheese melt on top.
Serve the burgers on hamburger buns with your favorite burger toppings.
Notes
This is an extremely flavorful burger seasoning, and it also works well with ground beef, ground chicken, ground turkey, or even ground pork!
Change up the flavor of your burgers by trying different spices and seasonings.
I suggest not cooking these over medium-well (155°F) as venison meat tends to dry out, about 3-5 minutes per side.
Ground venison is very similar in taste to ground beef, so it works well in dishes that call for ground beef.